16th World Cardiology Congress
Zigzag University, Egypt
Title: Differentiation of left ventricular global longitudinal strain between (controlled and uncontrolled) diabetic patients by speckle tracking imaging
Biography: Ahmed Abd-Elwahab Algohary
Introduction: Diabetic patients with normal left ventricular ejection fraction are frequently associated with diastolic dysfunction .Speckle tracking is more sensitive than LVEF in detection subclinical LV systolic dysfunction. However, it is not clear whether there is any difference in early LV systolic dysfunction between DM patients if they have controlled or uncontrolled blood glucose.
Aim: Detection of different patterns of global longitudinal strain in diabetic non ischemic patients either controlled or uncontrolled blood glucose level, using global longitudinal strain by speckle tracking.
Methods: fifty two diabetic patients had been referred from internal medicine clinic after they had been tested for HBA1c test and stratified into two groups
Group І: it include26 DM patients with controlled blood sugar.
Group ǁ: it include26 DM patients with uncontrolled blood sugar
The two groups had been subjected to the following diagnostic workup:
Full medical history, full clinical examination, laboratory assessment , twelve lead resting ECG ,Stress ECG, Echocardiography study, Traditional Tissue Doppler imaging ,Assessment of global longitudinal strain.
Patients with IHD, Systolic dysfunction, CHD ,Valvular, Arrhythmia, HOCM ,Pericardial, major systemic disease had been excluded.
Result: there was significant statistical difference in GLS, Age , Diabetic Type ,Diabetic Duration,2HPP Blood sugar level, E/é ratio in controlled DM compared to uncontrolled DM (p<0.05),there was no significant difference in Gender ,FBS. EF, E/A in controlled DM compared to uncontrolled DM.
Conclusion: Poor blood glucose control, as indicated by HbA1c>6.5%, leads to reductions in LV global longitudinal systolic strain, which is associated with preclinical LV dysfunction.