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16th World Cardiology Congress

Dubai, UAE

Sejla Sehovic

Sejla Sehovic

New Westminster College, Canada

Title: Highly sensitive troponin in myocardial ischemia during endoscopic retrograde cholangiopancreatography

Biography

Biography: Sejla Sehovic

Abstract

Background:   Procedural riks of ERCP are well recognized but  significance of cardiac risks remains controversial.This study aimed to evaluate ERCP-related highly sensitive cardiac troponin I (hs TnI) release in even small amounts of myocardial injury and to analyze potential relationship between myocardial ischemia and the development of post-ERCP pancreatitis.

Methods: 120 patients (aged 18-93 years) scheduled  for ERCP were enrolled in this study.Cardiovascular risk factors were identified in 60% of patients.All patients were  assessed clinically and with electrocardiography for the presence of ischemic disease before the procedure. Hs TNI ( limit of detection 1,9ng/l) was measured at baseline(pre- ERCP) , during ERCP and 2h post-ERCP.During ERCP procedure patients were also monitored with Holter tape rekorder.Amylase and lipase were measured before and 24 hours after ERCP.

Results: Twelve patients (12 %)developed myocardial ischemia/injury during ERCP with new ECG changes and  without any clinical symptom. 50 % of change in Hs TnI second measurement  was documented  in   12 patients (  p<0.01) .Patients with myocardial ischemia during ERCP had a significantly higher values of amylase and lipase levels(60,3%vs 16.2%; p<0.01)

Conclusions:The relationship was found between hs TnI  small elevation  and new ECG and  rythm changes on Holter during ERCP. Post ERCP pancreatitis was associated with myocardial ischemia/injury during ERCP.