Daniela Loncar
University Clinical Center Tuzla, Bosnia and Herzegovina
Title: Diastolic dysfunction of the left ventricle in dialysis patients
Biography
Biography: Daniela Loncar
Abstract
Purpose: The purpose of this study is to determine prevalence of diastolic dysfunction of the left ventricle in patients on chronic dialysis treatment and also determine prevalence of diastolic cardiac insufficiency in patients on chronic dialysis treatment.
Design & Methodology: A prospective study included 49 chronic dialysis patients (both hemodialysis and continuous ambulatory peritoneal dialysis). All patients had their medical history and electrocardiogram taken and underwent complete physical examination and echocardiography evaluation. Variables of diastolic dysfunction were determined by continuous (mitral inflow velocity) and pulse color Doppler patterns (pulmonary veins flow and motion of mitral annulus). Diagnostic criteria included symptoms of cardiac insufficiency (at rest or exertion), existence of diastolic dysfunction determined by echocardiography.
Results: In the study, a total of 49 patients were observed: 23 men (46.93%) and 26 women (53.06%). The average age of the patients was 48.17±10.56 years and the average duration of dialysis treatment was 43.6±18.5 months. Diastolic dysfunction was verified by echocardiography in 10 (20.4%) patients that is in 7 (70%) women and 3 (30%) men, of the average age 58.8±8.53 years and the average duration of dialysis 42.8±17.9 months. All patients with diastolic dysfunction of the left ventricle had preserved systolic function of the left ventricle (normal ejection fraction). Diastolic cardiac insufficiency was diagnosed in 3 (6.12%) patients, that is in 2 women and 1 man. The average age of patients with diastolic cardiac insufficiency was 54±7.59 years and the average duration of dialysis treatment was 41.7±7.5 months.
Conclusion: There is a high prevalence of diastolic dysfunction of the left ventricle in chronic dialysis patients.